JX06 是一种选择性共价PDK抑制剂，抑制PDK1,PDK2和PDK3，IC50值分别为 49 nM，101 nM 和 313 nM。它以不可逆的方式与半胱氨酸残基共价结合来抑制PDK1活性，具有抗肿瘤活性。

JX06, a potent, selective and covalent PDK inhibitor, inhibits PDK1, PDK2 and PDK3 with IC50 of 49 nM, 101 nM and 313 nM respectively.

729-46-4

C10H16N2O2S4

324.51

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years