KPLH1130 是丙酮酸脱氢酶激酶特异性抑制剂,能够阻断巨噬细胞极化,减轻炎症反应,也可改善高脂饮食喂养小鼠的葡萄糖耐受性。
产品描述
KPLH1130 improves glucose tolerance in HFD-fed mice. KPLH1130 is a specific pyruvate dehydrogenase kinase (PDK) inhibitor, blocks macrophage polarization and attenuates proinflammatory responses.
Cas No.
906669-07-6
分子式
C15H13N3O3
分子量
283.28
储存和溶解度
DMSO:130 mg/mL (458.91 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years