CCG-222740 是一种口服有效的选择性Rho/MRTF途径抑制剂。它也是 α-平滑肌的肌动蛋白表达抑制剂，可减少皮肤纤维化并阻止黑色素瘤转移。

CCG-222740 is an inhibitor of Rho/MRTF pathway

CCG-222740 decreases the activation of stellate cells in vitro and in vivo, by reducing the levels of alpha smooth muscle actin(α-SMA) expression[1].

1922098-69-8

C23H19ClF2N2O3

444.86

DMSO:125 mg/mL (280.99 Mm)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years