Toyocamycin是放线菌类产生的腺苷类似物，为 X 盒结合蛋白 1 (XBP1) 抑制剂，抑制 IRE1α 诱导的 ATP 依赖性 XBP1 mRNA 的断裂，IC50值为 80 nM。它还诱导凋亡。

Toyocamycin is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis.

606-58-6

C12H13N5O4

291.26

Vengicide;丰加霉素

DMSO:100 mg/mL (343.34 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years