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Lusianthridin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Lusianthridin图片
CAS NO:87530-30-1
包装与价格:
包装价格(元)
5 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
Lusianthridin 是来自石斛Dendrobium venustum的天然产物。 Lusianthridin 在无毒浓度下表现出抗迁移特性。 Lusianthridin 通过抑制 Src-STAT3 信号传导增强 c-Myc 降解。

产品描述

Lusianthridin is a natural product from Dendrobium venustum. Lusianthridin exhibits anti-migratory property at nontoxic concentrations. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signaling.

体外活性

Lusianthridin showed appreciable cytotoxicity against human lung cancer cell lines with IC50 values of 65.0 μg/mL[1]. Lusianthridin (0-100 μM) inhibited cell viability at concentrations greater than 50 μM in both H460 and H292 cells[2]. Lusianthridin significantly reduced the CSC populations in both H460 and H292 cells of the CSC spheres, with a significant decrease in the size of the H460 CSC spheres by approximately 10%, 63%, and 77% at day 3 at concentrations of 5, 10, and 20 μM, respectively[2].

Cas No.

87530-30-1

分子式

C15H14O3

分子量

242.27

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years