您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Metoprine
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Metoprine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Metoprine图片
CAS NO:7761-45-7
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
25 mg电议

产品介绍
Metoprine 是一种有效的组胺 N-甲基转移酶抑制剂,具有抗肿瘤活性。它是一种二氨基嘧啶衍生物,可以透过血脑屏障,并通过抑制 HMT 增加脑组胺水平。

产品描述

Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.

体内活性

In mammals, histamine N-methyltransferase (HMT) is the sole enzyme responsible for degrading histamine in the brain.?Metoprine, one of the most potent HMT inhibitors, can cross the blood-brain barrier and increase brain histamine levels by inhibiting HMT.?Consequently, this compound can be a candidate for a prototype of drugs for the treatment of METH overdose[1].

Cas No.

7761-45-7

分子式

C11H10Cl2N4

分子量

269.13

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years