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CYM50308
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CYM50308图片
CAS NO:1345858-76-5
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
CYM50308 是选择性和高亲和力的鞘氨醇-1-磷酸受体 4 激动剂,EC50为 56 nM。它对 S1P4-R 的选择性比 S1P5-R 高 37 倍。

产品描述

CYM50308 is a high affinity agonist of sphingosine-1-phosphate receptor 4 (S1P4-R) (EC50: 56 nM). CYM50308 has no activity at S1P1-R, S1P2-R and S1P3-R subtypes at concentrations up to 25 μM and it shows 37-fold more selective for S1P4-R than S1P5-R.

体外活性

CYM50308 shows low nanomolar S1P4-R agonist activity and exquisite selectivity over the other S1P-Rs subtypes. CYM50308 provides a valuable pharmacological tool to explore the effects of the S1P4-R signaling cascade and elucidate the molecular basis of the in vivo receptor function[1].

Cas No.

1345858-76-5

分子式

C20H21F2N3O2S

分子量

405.46

储存和溶解度

DMSO:12 mg/mL (29.60 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years