Yangambin 是从诸如番荔枝科植物中分离出来的呋喃木脂素，是选择性PAF受体拮抗剂，通过调控Ca2+通道抑制 Ca2+流入，导致 [Ca2+]i在血管平滑肌细胞和随后的外周血管舒张中减少，具有降压作用。

Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibition the Ca2+ influx through voltage-gated Ca2+ channels. Yangambin has central nervous system activity, it presents a depressant activity in the open field, forced swimming and pentobarbital sleeping time tests.

13060-14-5

C24H30O8

446.49

DMSO:60 mg/ml (134.38 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years