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Boc-NH-PEG5-CH2CH2COOH
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Boc-NH-PEG5-CH2CH2COOH图片
CAS NO:1347750-78-0
包装:250mg
市场价:3150元

产品介绍
Boc-NH-PEG5-CH2CH2COOH是一种基于PEG的PROTAClinker,用于合成PROTAC。
Cas No.1347750-78-0
别名N-叔丁氧羰基-五聚乙二醇-羧酸
Canonical SMILESO=C(OC(C)(C)C)NCCOCCOCCOCCOCCOCCC(O)=O
分子式C18H35NO9
分子量409.47
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Boc-NH-PEG5-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Nathanael Gray, et al. Bifunctional compounds for her3 degradation and methods of use. WO2017117474A1.