CAS NO: | 1347750-78-0 |
包装: | 250mg |
市场价: | 3150元 |
Cas No. | 1347750-78-0 |
别名 | N-叔丁氧羰基-五聚乙二醇-羧酸 |
Canonical SMILES | O=C(OC(C)(C)C)NCCOCCOCCOCCOCCOCCC(O)=O |
分子式 | C18H35NO9 |
分子量 | 409.47 |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Boc-NH-PEG5-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. [1]. Nathanael Gray, et al. Bifunctional compounds for her3 degradation and methods of use. WO2017117474A1. |