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Urocortin,human
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:176591-49-4
包装与价格:
包装价格(元)
5 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Human urocortin
Urocortin (human)
Human urocortin I
Human urocortin 1
产品介绍
Urocortin, human 是由 40 个氨基酸组成的神经多肽,是选择性CRF2受体激动剂,作用于 hCRF1(Ki:0.4 nM)、rCRF2α(Ki:0.3 nM)、 mCRF2β(Ki:0.5 nM)。

产品描述

Urocortin (Ucn) is a 40 amino acid peptide which is closely related to corticotrophin-releasing factor (CRF).

体外活性

Urocortin, human is a selective agonist of CRF2?receptor, with Kis of 0.4, 0.3, and 0.5 nM for human CRF1, rat CRF2α?and mouse CRF2β?receptors in cell assay, respectively[1].

体内活性

Urocortin (0.01 to 10 μg) decreases food intake in both food-deprived and non-deprived rats and such a effect also observed in mice after 1 μg of Urocortin i.c.v. administration. It appears to be a more potent suppressor of ingestive behavior. Urocortin has the potential of inducing anxiogenic behavior[2].

Cas No.

176591-49-4

分子式

C204H337N63O64

分子量

4696.32

别名

Human urocortin;Urocortin (human);Human urocortin I;Human urocortin 1

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years