Urocortin (rat) acetate 是一种内源性 CRFR 激动剂,对人 CRF1、大鼠 CRF2α 和小鼠 CRF2β 的 Ki 分别为 13 nM、1.5 nM 和 0.97 nM。 Urocortin (rat) acetate 是一种神经肽。
产品描述
Urocortin (rat) acetate is an agonist of endogenous CRFR with Kis of 13 nM, 1.5 nM, and 0.97 nM for human CRF1, rat CRF2α and mouse CRF2β, respectively. Urocortin (rat) acetate is a neuropeptide.
体外活性
Urocortin (rat) acetate induces cAMP generation with EC50 of 0.15 nM, 0.063 nM, and 0.087 nM for human CRF1, rat CRF2α and mouse CRF2β, respectively in stably transfected Chinese hamster ovary cells[1].
体内活性
Urocortin (rat) acetate (0.01 to 10 μg) decreases food intake in both food-deprived and non-deprived rats and such an effect was observed in mice after Urocortin (1 μg; i.c.v.) administration[2].
别名
Urocortin (rat) acetate (171543-83-2 Free base)
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years