(Ala13)-Apelin-13 acetate,一种APJ拮抗剂,可调节CRF诱导的增强的结肠运动、内脏敏感性和肠屏障。
产品描述
(Ala13)-Apelin-13 acetate, an APJ antagonist, modulates CRF-induced enhanced colonic motility, visceral sensation, and gut barrier.
体内活性
(Ala13)-Apelin-13 acetate (i.p.)blocked lipopolysaccharide (LPS)- or CRF-induced visceral hypersensitivity and colonic hyperpermeability (IBS model) in a dose-response manner[1].
Cas No.
T35374L
分子式
C65H111N23O18S
分子量
1534.79
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years