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Boc-NH-PEG4-CH2CH2NH2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Boc-NH-PEG4-CH2CH2NH2图片
CAS NO:811442-84-9
包装:100mg
市场价:1350元

产品介绍
Boc-NH-PEG4-CH2CH2NH2是一种可降解(cleavable)的5单元PEG类ADClinker,用于抗体偶联药物(ADC)的合成。
Cas No.811442-84-9
别名16-氨基-5,8,11,14-四氧杂-2-氮杂十六烷酸1,1-二甲基乙酯
Canonical SMILESO=C(OC(C)(C)C)NCCOCCOCCOCCOCCN
分子式C15H32N2O6
分子量336.42
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Boc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[1]. Hans-Georg Lerchen, et al. Preparation of antibody drug conjugates of kinesin spindle protein (KSP) inhibitors with anti-TWEAKR-antibodies. WO2016207094A1.