CAS NO: | 108466-89-3 |
包装: | 100mg |
市场价: | 900元 |
Cas No. | 108466-89-3 |
别名 | 2-[2-(叔丁氧羰基氨基)乙氧基]乙氧基乙酸 |
Canonical SMILES | CC(C)(C)OC(NCCOCCOCC(O)=O)=O |
分子式 | C11H21NO6 |
分子量 | 263.29 |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. [1]. Zhou F, et al. Development of selective mono or dual PROTAC degrader probe of CDK isoforms. Eur J Med Chem. 2020 Feb 1;187:111952. |