Praliciguat 是一种有效且具有口服活性的可溶性鸟苷酸环化酶 (sGC) 刺激剂，还增强 NO 信号传导，可作为血管扩张剂。在 HEK-293 细胞中，它能够刺激 sGC，EC50值为 197 nM。

Praliciguat stimulates sGC in HEK-293 cells (EC50: 197 nM). Praliciguat is an effective and orally active soluble guanylate cyclase stimulator. It also enhances NO signaling and acts as a vasodilator.

1628730-49-3

C21H14F8N6O2

534.36

IW-1973

DMSO:245 mg/mL (458.50 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years