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BCN-PEG4-acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BCN-PEG4-acid图片
CAS NO:1881221-47-1
包装与价格:
包装价格(元)
50mg电议
250mg电议

产品介绍
BCN-PEG4-acid是一种可降解(cleavable)的含4个单元PEG的ADClinker,可用于合成抗体偶联药物(ADC)。
Cas No.1881221-47-1
Canonical SMILESO=C(O)CCOCCOCCOCCOCCNC(OC[C@H]1[C@@]2([H])CCC#CCC[C@@]12[H])=O
分子式C22H35NO8
分子量441.52
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

BCN-PEG4-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.