产品描述
GRKs-IN-1 hydrochloride has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50: 130 nM) and GRK5 (IC50: 7.1 μM).
体外活性
GRKs-IN-1 hydrochloride (Compound 14as) is a derivative 14as of paroxetine, shows a 100-fold improvement in cardiomyocyte contractility assays over paroxetine.
Cas No.
T13714L
分子式
C24H26ClFN4O4
分子量
488.94
别名
GRK2-IN-1 hydrochloride
储存和溶解度
DMSO:250 mg/mL (511.31 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years