Melanin Concentrating Hormone, salmon acetate(87218-84-6 free base) 是一种 19 个氨基酸的环状肽，主要在下丘脑中表达。

Melanin Concentrating Hormone, salmon acetate is a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus.

An orphan G protein-coupled receptor (SLC-1/GPR24) has been identified as a receptor for MCH (MCHR1). MCHR2 has higher protein sequence homology to MCHR1 than any other G protein-coupled receptor. MCHR2 is specifically activated by nanomolar concentrations of MCH, binds to MCH with high affinity, and signals through Gq protein[1].

Melanin Concentrating Hormone stimulates appetite. Continuous infusion of Melanin Concentrating Hormone into the ventricular system increases food intake for 7-8 days[2]. Intracerebroventricular infusion of Melanin Concentrating Hormone (10 μg/day) causes a slight but significant increase in body weight in mice maintained on the regular diet. Chronic stimulation of the brain Melanin Concentrating Hormone system could cause obesity in mice[3].

TP1104L

C91H143N27O26S4

2157

MCH (salmon);Melanin Concentrating Hormone, salmon acetate(87218-84-6 free base)

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years