MCHR1 antagonist 2 是有效的黑色素聚集激素受体 1 拮抗剂，IC50为 65 nM。它也抑制HERG，在IMR-32 细胞中的IC50为 4.0 nM。

MCHR1 antagonist 2 is an antagonist of melanin-concentratin hormone receptor 1(MCH1-R, IC50 = 65 nM) and also inhibits hERG.

MCHR1 antagonist 2 has inhibitory effects on Ca2+?flux, and hERG, with IC50s of 196?±?30 nM and 4.0?±?0.8 nM, respectively, in IMR-32 cells.MCHR1 antagonist 2 is an antagonist of melanin concentrating hormone receptor 1, with an IC50 of 65 nM.

863115-70-2

C23H21FN2O5

424.42

DMSO:9 mg/mL (21.21 mM),ultrasonic and adjust pH to 6 with HCl
Powder: -20°C for 3 years
In solvent: -80°C for 2 years