5-Hydroxy-7,8-dimethoxyflavanone 是从穿心莲叶和根中分离出来的,具有抗炎活性。
产品描述
5-Hydroxy-7,8-dimethoxyflavanone is isolated from Andrographis paniculata Nees. leaves and roots with anti-inflammatory activity.
体外活性
5-Hydroxy-7,8-dimethoxyflavanone efficiently increased the susceptibility of CYP6AA3- and CYP6P7-expressing Spodoptera frugiperda (Sf9) cells to cypermethrin toxicity, due to inhibition effects on mosquito enzymes[1]. 5-Hydroxy-7,8-dimethoxyflavanone significantly decreases TNF-alpha, IL-6, macrophage inflammatory protein-2 (MIP-2), and nitric oxide (NO) secretions from LPS/IFN-gamma stimulated RAW 264.7 cells[2].
Cas No.
113981-49-0
分子式
C17H16O5
分子量
300.31
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years