Methylthiouracil 是一种抗甲状腺剂。它抑制TNF-α和IL-6的产生以及NF-Κb和ERK1/2的活化。

Methylthiouracil is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.

Methylthiouracil acts to decrease the formation of stored thyroid hormone, as thyroglobulin in the thyroid gland. Methylthiouracil is also used in combination with radioactive iodine.

56-04-2

C5H6N2OS

142.18

NSC-9378;甲基硫脲嘧啶;甲硫氧嘧啶;NSC-193526;MTU

DMSO:27 mg/mL (189.9 mM)
Ethanol:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years