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Durvalumab
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1428935-60-7
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
25 mg电议
50 mg电议
100 mg电议

产品名称
德瓦鲁单抗
MEDI 4736
产品介绍

产品描述

Durvalumab is an anti-PD-L1 monoclonal antibody, humanized.Durvalumab completely blocked the binding of PD-L1 to PD-1 and CD80, and the IC50s were 0.1 and 0.04 nM, respectively.

体内活性

Durvalumab inhibits tumor growth in a mouse xenograft model of human melanoma (A375) and pancreatic (HPAC) tumor cell lines through a T-cell-mediated mechanism.The tumor growth inhibition of HPAC cells was 74% and that of A375 cells was 77%.Durvalumab had no effect on the growth of the A375 xenograft tumor in the absence of T cells.

Cas No.

1428935-60-7

别名

德瓦鲁单抗;MEDI 4736