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rel-α-Vitamin E
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
rel-α-Vitamin E图片
CAS NO:2074-53-5
包装与价格:
包装价格(元)
rel-汐-Vitamin E 10mM (in 1mL Water)电议
10mg电议

产品介绍

rel-α-Vitamin E (rel-D-α-Tocopherol ) 是一种具有抗氧化特性的维生素,也是一种混合物。

Cas No.2074-53-5
别名维生素E,rel-D-α-Tocopherol
Canonical SMILESOC1=C(C)C(C)=C2C(CC[C@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)O2)=C1C.[Relative stereochemistry]
分子式C29H50O2
分子量430.71
溶解度Ethanol: 50 mg/mL (116.09 mM); DMSO: 16.11 mg/mL (37.40 mM)
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

rel-α-Vitamin E (rel-D-α-Tocopherol ) is a vitamin with antioxidant properties and also a mixture[1].

Vitamin E is a lipid-soluble, chain-breaking type of antioxidant present in human blood. Vitamin E works as a free radical scavenger and has the primary function of destroying peroxyl radicals. Thus, it protects long-chain polyunsaturated fatty acids (e.g., cell membranes or low-density lipoprotein cholesterol) from oxidation or destruction. Its association with vitamin C is of great pathophysiological importance, because inhibition of lipid peroxidation by α-tocopherol occurs through its conversion into an oxidized α-tocopheroxyl radical, which in turn is regenerated to α-tocopherol through reduction by redox-active reagents[1].α-Tocopherol can inhibit the recruitment of lymphocytes and eosinophils[1].

In order to longitudinally relate vitamin E status, evaluated by means of α- and γ-tocopherol measured in erythrocytes membranes, to inflammatory state and oxidative stress by means of total antioxidant capacity of plasma and lipid peroxidation biomarkers, and to assess its association to hard long-term outcomes (e.g., overall and cause-specific graft and recipient loss), and to be able to likewise account for liver, lung, and heart transplant recipients[1].

[1]. Sotomayor CG, et al. Plasma versus Erythrocyte Vitamin E in Renal Transplant Recipients, and Duality of Tocopherol Species. Nutrients. 2019 Nov 19;11(11). pii: E2821.