BM-PEG3 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
BM-PEG3 is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
86099-06-1
分子式
C16H20N2O7
分子量
352.34
别名
1,11-双马来酰亚胺基-3,6,9-三氧代十一烷;1,11-Bis-maleimidotetraethyleneglycol
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years