dBET57 是基于 PROTAC 技术的 BRD4 异双功能降解剂，对 BRD4BD1 有显著降解作用，DC50/5h 为 500 nM。

dBET57 is heterobifunctional degrader of BRD4 based on the PROTAC technology, exhibits significant degradation of BRD4BD1 with a DC50/5h of 500 nM ,and inactive on BRD4BD2

1883863-52-2

C34H31ClN8O5S

699.18

DMSO:250 mg/mL (357.56 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years