Kamebakaurin 是一种提取自Isodon japonicus中的天然产物，是一种NF-Κb的抑制剂，能够抑制 p50 的 DNA 结合活性。

1. Kamebakaurin has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression of hypoxia-inducible factor-1α and its target genes to confer antitumor activity. 3. Kamebakaurin has anti-cancer and anti-inflammatory activities through direct inhibition of DNA-binding activity of nuclear factor-kappa B (NF-κB) p50.4. Kamebakaurin has anti-neuroinflammatory activity via inhibition of c-Jun NH -terminal kinase and p38 mitogen-activated protein kinase pathway in activated microglial cells.

73981-34-7

C20H30O5

350.455

Kamebakaurine;尾叶香茶菜丙素

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble
DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years