PA452 是视黄酸 X 受体 (RXR) 的选择性拮抗剂，可抑制视黄酸对 Th1/Th2 发育的影响。

PA452 is a selective antagonist of retinoic X receptor (RXR) and suppresses the effect of Retinoic acid on Th1/Th2 development.

PA452 suppresses the Troglitazone (TZ)-induced CK13 expression. In normal human urothelial (NHU) cells, PA452 (0.01-1 μM) inhibits retinoic X receptor[2].

457657-34-0

C26H37N3O3

439.59

Ethanol:4.4 mg/mL (10.01 mM),Need ultrasonic and warming
DMSO:36mg/mL (81.9mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years