Gallopamil hydrochloride 是苯烷基胺钙的拮抗剂。Gallopamil hydrochloride 可用于抗心律失常和血管扩张剂研究。
产品描述
Gallopamil hydrochloride is an antagonist of phenylalkylamine calcium. Gallopamil hydrochloride can be used in antiarrhythmic and vasodilator studies.
体外活性
Gallopamil hydrochloride inhibits acid secretion in a concentration-dependent manner with an IC50 of 10.9 μM[1].
体内活性
In male Wistar rats, Gallopamil hydrochloride (0.2 mg/kg; i.v. for 5 min) markedly reduces ventricular tachycardia and totally prevents fibrillation. Gallopamil hydrochloride significantly reduces systolic and diastolic blood pressure measured 5 min after injection without markedly influencing heart rate[2].
Cas No.
16662-46-7
分子式
C28H41ClN2O5
分子量
521.09
别名
Methoxyverapamil hydrochloride
储存和溶解度
DMSO:95 mg/mL?(182.31 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years