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mesaconine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
mesaconine图片
CAS NO:6792-09-2
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议

产品介绍
Mesaconine 是来自 Aconitum carmichaelii Debx 的一种成分。Mesaconine 具有心脏作用和抗 NF-Κb 活性。 Mesaconine可能是麻黄附子细辛汤抗炎和免疫抑制的部分物质基础。

产品描述

Mesaconine is an ingredient from Aconitum carmichaelii Debx.. Mesaconine has a cardiac effect and anti-NF-κB activity. Mesaconine may be part of the material basis of Mahuang Fuzi Xixin decoction on anti-inflammation and immune suppression.

体外活性

The anti-inflammatory effect of SFI was verified in vitro with endothelial cells. After detecting the cell viability, the expression of interleukin-6 (IL-6), inhibitor of nuclear factor kappa-B kinase (IKK), phosphorylated IKK, phosphorylated NF-κB and phosphorylated IκB-α± from the supernatant were determined. SFI could significantly suppress inflammatory responses, and the mechanism may be via an NF-κB-dependent pathway. Mesaconine is the first reported SFI compounds to have NF-κB inhibitor activity[1].

Cas No.

6792-09-2

分子式

C24H39NO9

分子量

485.574

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years