CB2 receptor agonist 2 是有效和选择性的 CB2 受体激动剂。对 CB2 的 Ki 为 8.5 nM。CB2 receptor agonist 2 对 CB2 具有高亲和力和选择性。

CB2 receptor agonist 2 is a potent and selective agonist for the CB2 (cannabinoid type 2) receptor, Ki = 8.5 nM. CB2 receptor agonist 2 has high affinity and selectivity for CB2.

CB2 receptor agonist 2 (compound 4g) (1 μM; 72 hours) shows low or no cytotoxicity to Hep-G2 cells[1].

CB2 receptor agonist 2 (compound 4g) (1 and 3 mg/kg; 1 hour) is very potent (with maximal effect being reached already at the 1 mg/kg dose) and has antihyperalgesic effects, efficacious also on the first phase of the nocifensive response and strongly reduced by AM630, a CB2-selective antagonist/inverse agonist [1].

1314230-75-5

C30H36N2O4

488.62

CB2受体拮抗剂2;ZINC72105556;4-Quinolone-3-Carboxamide Furan CB2 Agonist

DMSO:3mg/mL (6.1mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years