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Gypsogenin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Gypsogenin图片
CAS NO:639-14-5
包装与价格:
包装价格(元)
5 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
丝石竹皂苷元
产品介绍
Gypsogenin 是一种天然存在的生化物质,具有明显的抗血管生成活性和对 H460 的细胞毒性,拥有抗 ABL1 激酶和抗慢性骨髓性白血病作用。

产品描述

Gypsogenin is a naturally occurring biochemical that shows anti-ABL1 kinase and anti-chronic Myelogenous Leukemia activities.

体外活性

Gypsogenin (1) was obtained by acidic hydrolysis from its saponin.?While the parent compound 1 acted as a selective inhibitor for butyrylcholinesterase (from equus) possessing a moderate mixed-type inhibition of the enzyme, Ki values as low as 2.67 0.59 μM were determined for (3β,4α) 3-O-acetyl-olean-12-ene-23,28-dinitrile (11) and acetylcholinesterase (AChE, from electric eel).?Thus, 11 possesses one-fifth of the inhibitory activity of the "gold standard" galantamine hydrobromide;?this compound is one of the first pentacyclic triterpenoids described as a potent AChE-selective inhibitor

Cas No.

639-14-5

分子式

C30H46O4

分子量

470.68

别名

639-14-5;丝石竹皂苷元

储存和溶解度

DMSO:27.5 mg/ml (58.42 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years