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HIV-1 integrase inhibitor 8
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
HIV-1 integrase inhibitor 8图片
CAS NO:1568-80-5
包装与价格:
包装价格(元)
50 mg电议
100 mg电议
200 mg电议
500 mg电议

产品介绍
HIV-1 Integrase inhibitor 8是HIV-1整合蛋白酶抑制剂。

产品描述

HIV-1 integrase inhibitor 8 is a HIV-1 integrase inhibitor.

体外活性

HIV-1 integrase inhibitor 8 were tested against 3′-processing (TC) and strand-transfer (ST) activities in the presence of Mn2+ as the cationic cofactor by gel assay, IC50=275μM and 231μM, respectively. HIV-1 integrase inhibitor 8 were retested using Mg2+ and the IC50 of against strand-transfer (ST) activities was 200μM. HIV-1 integrase inhibitor 8 inhibits MCV topoisomerase and DNA religation with IC50 of 500 μM and 200 μM, respectively. HIV-1 integrase inhibitor 8 induces cell cytotoxicity with LD50 of 20 μM in HeLa cells[1].

Cas No.

1568-80-5

分子式

C21H24O2

分子量

308.41

储存和溶解度

DMSO:112.5mg/mL (364.8mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years