5,?7,?4'-?Trimethoxyflavone 是从泰国著名的药用植物Kaempferia parviflora中分离出来的一种天然产物。它以浓度依赖性方式显著有效抑制 SNU-16 人胃癌细胞的增殖,诱导细胞凋亡。
产品描述
5,7,4'-Trimethoxyflavone is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.
体外活性
5,7,4'-Trimethoxyflavone induces apoptosis, as evidenced by increments of sub-G1 phase, DNA fragmentation, annexin-V/PI staining, the Bax/Bcl-xL ratio, proteolytic activation of caspase-3, and degradation of PARP protein. 5,7,4'-Trimethoxyflavone is significantly effective at inhibiting the proliferation of SNU-16 human gastric cancer cells in a concentration-dependent manner.
Cas No.
5631-70-9
分子式
C18H16O5
分子量
312.321
别名
4',5,7-Trimethoxyflavone;5,7,4'-三甲氧基黄酮;芹菜素三甲醚;4',5,7-三甲氧基黄酮
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years