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Crocin II
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Crocin II图片
CAS NO:55750-84-0
包装与价格:
包装价格(元)
20 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Crocin B
西红花苷II
藏红花
Crocin 2
Crocetin gentiobiosylglucosyl ester
Tricrocin
产品介绍
Crocin II 是从栀子果实中分离出来的一种天然产物,具有抗氧化、抗癌和抗抑郁活性。它抑制iNOS和COX-2的蛋白质和 m-RNA 的表达,还抑制NO产生,IC50值为 31.1 μM。

产品描述

Crocin has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expression of iNOS and caspase-3. Crocin can ameliorate CCl4-induced liver injury via inhibition of inflammatory cytokines, caspase3 and oxidative stress along with modulation of liver metabolizing enzymes favoring elimination of CCl4 toxic metabolite. Crocin has antihyperlipidemic effect, may be due to the inhibition of pancreatic lipase and crocin, and its metabolite, crocetin, can improve hyperlipidemia. Crocin has antidepressant effects by increasing CREB, BDNF and VGF levels in hippocampus.

Cas No.

55750-84-0

分子式

C38H54O19

分子量

814.831

别名

Crocin B;西红花苷II;藏红花;Crocin 2;Crocetin gentiobiosylglucosyl ester;Tricrocin

储存和溶解度

DMSO:122.7 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years