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Bacoside A3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bacoside A3图片
CAS NO:157408-08-7
包装:5 mg
市场价:950元

产品名称
苦艾素A3
白花猪母菜甙 A3
产品介绍
Bacoside A3 是一种天然的三萜皂苷,是Bacopa monnieri的主要活性成分之一,显示出神经保护活性。

产品描述

Bacoside A3 is one of the components of Bacopa monnieri (L.) Wettst. bacoside A with antioxidant potential. Bacoside A3 shows comparatively higher neuroprotective response analysed as higher cell viability and decreased intracellular ROS.

体外活性

The cytoprotective effects of individual bacoside A components were evaluated towards oxidative stressed neuronal cells. Bacoside A was screened for neuronal cell viability (MTT assay) and change in intracellular reactive oxygen species (ROS), anti-apoptotic properties and mitochondrial membrane potential (MMP) using fluorescence microscopy. Different bacoside A components showed decrease in N2a cell viability below 100 (%) after bacoside A concentration of 0.4 mg/ml. Further, cytoprotective effect of optimized dose of bacoside A was analysed for alleviating oxidative stressed, apoptosis and MMP in H2 O2 stressed neuronal cells. Results showed increase in MMP, and decrease in apoptotic induction, without much change in nuclear integrity in stressed neuronal cells. Results showed Bacoside A3 and bacopaside II have comparatively higher cytoprotective ability whilst isomer of bacopasponin C, bacopasaponin C and mixture showed comparatively less response[1]

Cas No.

157408-08-7

分子式

C47H76O18

分子量

929.1

别名

苦艾素A3;白花猪母菜甙 A3

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years