Bacoside A3 是一种天然的三萜皂苷，是Bacopa monnieri的主要活性成分之一，显示出神经保护活性。

Bacoside A3 is one of the components of Bacopa monnieri (L.) Wettst. bacoside A with antioxidant potential. Bacoside A3 shows comparatively higher neuroprotective response analysed as higher cell viability and decreased intracellular ROS.

The cytoprotective effects of individual bacoside A components were evaluated towards oxidative stressed neuronal cells. Bacoside A was screened for neuronal cell viability (MTT assay) and change in intracellular reactive oxygen species (ROS), anti-apoptotic properties and mitochondrial membrane potential (MMP) using fluorescence microscopy. Different bacoside A components showed decrease in N2a cell viability below 100 (%) after bacoside A concentration of 0.4 mg/ml. Further, cytoprotective effect of optimized dose of bacoside A was analysed for alleviating oxidative stressed, apoptosis and MMP in H2 O2 stressed neuronal cells. Results showed increase in MMP, and decrease in apoptotic induction, without much change in nuclear integrity in stressed neuronal cells. Results showed Bacoside A3 and bacopaside II have comparatively higher cytoprotective ability whilst isomer of bacopasponin C, bacopasaponin C and mixture showed comparatively less response[1]

157408-08-7

C47H76O18

929.1

苦艾素A3;白花猪母菜甙 A3

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years