CAS NO: | 147127-19-3 |
规格: | ≥98% |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
250mg | 电议 |
(S)-Tenofovir [known also as (S)-GS 1278], the S-enantiomer of Tenofovir and a less active isomer, is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV). Tenofovir
(formerly also known as GS-1278; PMPA; TDF) is an approved anti-HIV drug
that blocks reverse transcriptase and hepatitis B virus infections.
Tenofovir is an antiretroviral medication used to prevent and treat
HIV/AIDS and to treat chronic hepatitis B. Tenofovir reduces the viral
cytopathic effect of HIV-1(IIIB), HIV-2(ROD) and HIV(EHO) with EC50 of
1.15 μg/mL, 1.12 μg/mL and 1.05 μg/mL in MT-4 cells. Tenofovir also
reduces the viral cytopathic effect of SIV(mac251) , SIV(B670)
,SHIV(89.6) and SHIV(RTSHIV). Tenofovir is the active substance of
tenofovir disoproxil which is a prodrug that is used because of its
better absorption in the gut. References: [1]. Murphy RA, et al. Establishment of HK-2 Cells as a Relevant Model to Study Tenofovir-Induced Cytotoxicity. Int J Mol Sci. 2017 Mar 1;18(3).
纯度:≥98%
CAS:147127-19-3