Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent proSTATe cancer cell growth through activation of cell Apoptosis and downregulation of Androgen Receptor expression. Physalin A induces Apoptosis via p53-Noxa-mediated ROS generation, and Autophagy plays a protective role against Apoptosis through p38-NF-?oB survival pathway in A375-S2 cells.

Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate cancer cell growth through activation of cell apoptosis and downregulation of androgen receptor expression. Physalin A induces apoptosis via p53-Noxa-mediated ROS generation, and autophagy plays a protective role against apoptosis through p38-NF-IoB survival pathway in A375-S2 cells.

23027-91-0

C28H30O10

526.538

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years