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Lirinidine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Lirinidine图片
CAS NO:54383-28-7
包装与价格:
包装价格(元)
10 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
Lirinidine 是一种分离自L. tulipifera叶片生物碱,具有抗氧化 (Antioxidant) 和抗癌作用。它在体外表现出中等的铁还原能力和较小的自由基清除能力,可用于研究化妆品。

产品描述

(+)-Lirinidine has antioxidative activity, and it can significantly inhibit the proliferation of melanoma cells; it also shows potent inhibition of melanogenesis. Lirinidine exhibits significant inhibition of collagen, arachidonic acid and platelet-activating factor-induced platelet aggregation.

体外活性

Sixteen compounds were extracted and purified from the leaves of Liriodendron tulipifera. These compounds include aporphines, oxoaporphine, coumarin, sesquiterpene lactone, benzenoids, cyclitol and steroids. (+)-Norstephalagine (2) (an aporphine) and scopoletin (8) (a coumarin) were isolated from Liriodendron tulipifera leaves from the first time. The identified compounds were screened for their antiradical scavenging, metal chelating and ferric reducing power activities. The results have showed that these compounds have antioxidative activity. The study has also examined the chemopreventive property of the isolated compounds against human melanoma cells A375. The results showed that (-)-anonaine (1), (-)-liridinine (3), (+)-Lirinidine (6), lysicamine (7) and epitulipinolide diepoxide (9) significantly inhibited the proliferation of melanoma cells[1]

Cas No.

54383-28-7

分子式

C18H19NO2

分子量

281.35

储存和溶解度

DMSO:55 mg/ml (195.49 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years