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Robinetin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Robinetin图片
CAS NO:490-31-3
包装与价格:
包装价格(元)
5 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
3,3',4',5',7-Pentahydroxyflavone
洋槐黄素
产品介绍
Robinetin 是一种天然黄酮,具有显著的“两种颜色”固有荧光特性。它具有抗真菌、抗病毒、抗菌、抗突变、抗氧化和抗自由基活性,高效抑制 EYPC 膜脂质过氧化和 HbA 糖基化。

产品描述

Robinetin has antioxidant and antiradical activities, inhibits EYPC membrane lipid peroxidation and HbA glycosylation with high efficiency.

体外活性

Robinetin inhibits the DNA synthesis in Proteus vulgaris, and the RNA synthesis in S. aureus[2]. Robinetin exhibits photo-induced excited-state intramolecular proton transfer resulting in ‘two color’ (in ‘blue-violet’ and ‘yellow-green’ regions) fluorescence characteristic of flavonols, the relative contributions between the two colors being strongly modulated by the local environment of the fluorophore[3]. Robinetin (0.1-10 μM; 1 h) inhibits HIV integrase cleavage and integration in a dose-dependent manner[4].

体内活性

Pretreatment with 0.5, 12.5 or 25 mumol robinetin resulted in elevated induction of epidermal ODC by TPA at 6 h after TPA. However, treatment with 50 or 100 mumol robinetin diminished ODC induction at 6 h after TPA[2]. Anti-mutagenicity was determined in the Salmonella typhimurium assay, Robinetin caused an 87% inhibition of mutagenicity by 2-aminoanthracene[2]

Cas No.

490-31-3

分子式

C15H10O7

分子量

302.24

别名

3,3',4',5',7-Pentahydroxyflavone;洋槐黄素

储存和溶解度

DMSO:100 mg/mL (330.86 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years