Abrine 是一种吲哚胺-2,3-双加氧酶 (IDO) 抑制剂，可用于研究癌症。

Abrine exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse LLC cells at 200 mg/kg, induction of IDO1 protein expression in tumor of C57BL/6 mouse allografted with mouse LLC cells at 200 mg/kg, antitumor activity against mouse LLC cells allografted in C57BL/6 mouse, antiproliferative activity against mouse LLC cells at 50 uM.

21339-55-9

C12H14N2O2

218.25

相思子碱;相思豆碱;红豆;N-ME-Tryptophan;Abrine;L-Abrine

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years