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Poricoic acid B
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Poricoic acid B图片
CAS NO:137551-39-4
包装与价格:
包装价格(元)
10 mg电议
20 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
茯苓酸B
茯苓新酸 B
产品介绍
Poricoic acid B 是提取自Poria cocos中,拥有抗肿瘤作用。

产品描述

Poricoic acid B shows inhibitory activity against TPA-induced ear inflammatory oedema, it also shows potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA).

体外活性

These two, and eight other known compounds isolated from the sclerotium, Poricoic acid B (3), poricoic acid A (4), tumulosic acid (5), dehydrotumulosic acid (6), 3-epidehydrotumulosic acid (7), polyporenic acid C (8), 25-hydroxy-3-epidehydrotumulosic acid (9), and dehydroabietic acid methyl ester (10), showed potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). Evaluation of the cytotoxicity of compounds 1 and 4 against human cancer cell lines revealed that 1 was significantly cytotoxic to leukemia HL-60 cells [GI(50) (concentration that yields 50% growth) value 39.3 nM], although it showed only moderate cytotoxicity to the other cells. Compound 4 exhibited moderate cytotoxicity to all of the cancer cell lines tested.

Cas No.

137551-39-4

分子式

C30H44O5

分子量

484.67

别名

茯苓酸B;茯苓新酸 B

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years