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Polyporenic acid C
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Polyporenic acid C图片
CAS NO:465-18-9
包装与价格:
包装价格(元)
5 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
猪苓酸C
聚孔酸C
产品介绍
Polyporenic acid C 是从茯苓中分离出的一种羊毛甾烷型三萜,可通过死亡受体介导的凋亡途径诱导细胞凋亡,有用于肺癌的研究潜力。

产品描述

Polyporenic acid C shows inhibitory activity against human collagenase.

体外活性

Polyporenic acid C (PPAC) significantly reduced cell proliferation via induction of apoptosis as evidenced by sub-G1 analysis, annexin V-FITC staining, and increase in cleavage of procaspase-8, -3, and poly(ADP-ribose)-polymerase (PARP). However, unlike our previously reported lanostane-type triterpenoid, pachymic acid, treatment of cells with PPAC was not accompanied by disruption of mitochondrial membrane potential and increase in cleavage of procaspase-9. Further, PPC-induced apoptosis was inhibited by caspase-8 and pan-caspase inhibitors but not by a caspase-9 inhibitor.

Cas No.

465-18-9

分子式

C31H46O4

分子量

482.69

别名

猪苓酸C;聚孔酸C

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years