(Rac)-LM11A-31 diHCl is an isomer of LM11A-31 diHCl. LM11A-31 diHCl, a non-peptide p75NTR (neurotrophin receptor p75) modulator, is an orally bioavailable and highly potent proNGF (nerve growth factor) antagonist. References: [1]. Elshaer SL, et al. Modulation of the p75 neurotrophin receptor using LM11A-31 prevents diabetes-induced retinalvascular permeability in mice via inhibition of inflammation and the RhoA kinase pathway. Diabetologia. 2019 Aug;62(8):1488-1500.
纯度:≥98%
CAS:1214672-15-7