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Dauricine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dauricine图片
CAS NO:524-17-4
包装与价格:
包装价格(元)
20 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
Dauricine 是存在于北豆根粉末中的一种双苯异喹啉生物碱,具有抗炎活性。它通过抑制NF-Κb激活,剂量依赖性地抑制结肠癌细胞的增值和侵袭,并诱导凋亡。

产品描述

1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important role in the transportation of Dauricine across the blood-brain barrier. 3. Dauricine may has anti-tumor effect, can inhibit tumor cells in urinary system and colon cancer cell proliferation, invasion; induce cell apoptosis by suppressing NF-kappaB activity and the expression profile of its downstream genes.

Cas No.

524-17-4

分子式

C38H44N2O6

分子量

624.778

储存和溶解度

DMSO:91 mg/mL(145.7 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years