Rotundine 是多巴胺D1、D2和D3受体的拮抗剂，IC50值分别为 166、1.4 和 3.3 μM。 它也是5-HT1A的拮抗剂，IC50值为 370 nM。

Rotundine (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.

Cidofovir inhibits human cytomegalovirus (HCMV) infection in cultured cells. Cidofovir is inhibitory to CMV plaque formation even when added to the cells at 48 hr post infection with IC50 of 0.9 μg/mL for Davis and 1.6 μg/mL for AD-169 strains,respectively. [1] Cidofovir also inhibits herpes simplex virus infection. In addition, Cidofovir blocks cell fusion induced by HSV-1 in monkey kidney cells and blocks the expression of HSV-l-specific proteins and the synthesis of viral DNA. [3]

483-14-7

C21H25NO4

355.434

Gindarine;(-)-Tetrahydropalmatine;Caseanine;罗通定;L-Tetrahydropalmatine

DMSO:8 mg/mL (22.5 mM)
H2O:<1 mgml
Ethanol:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years