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Rotundine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Rotundine图片
CAS NO:483-14-7
包装与价格:
包装价格(元)
20 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Gindarine
(-)-Tetrahydropalmatine
Caseanine
罗通定
L-Tetrahydropalmatine
产品介绍
Rotundine 是多巴胺D1、D2和D3受体的拮抗剂,IC50值分别为 166、1.4 和 3.3 μM。 它也是5-HT1A的拮抗剂,IC50值为 370 nM。

产品描述

Rotundine (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.

体外活性

Cidofovir inhibits human cytomegalovirus (HCMV) infection in cultured cells. Cidofovir is inhibitory to CMV plaque formation even when added to the cells at 48 hr post infection with IC50 of 0.9 μg/mL for Davis and 1.6 μg/mL for AD-169 strains,respectively. [1] Cidofovir also inhibits herpes simplex virus infection. In addition, Cidofovir blocks cell fusion induced by HSV-1 in monkey kidney cells and blocks the expression of HSV-l-specific proteins and the synthesis of viral DNA. [3]

Cas No.

483-14-7

分子式

C21H25NO4

分子量

355.434

别名

Gindarine;(-)-Tetrahydropalmatine;Caseanine;罗通定;L-Tetrahydropalmatine

储存和溶解度

DMSO:8 mg/mL (22.5 mM)
H2O:<1 mgml
Ethanol:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years