DracoRhodin perochlorate 是来源于中药血竭的一种天然产物。它抑制细胞生长,并以剂量和时间依赖性方式诱导成纤维细胞凋亡,将细胞周期阻滞在 G1 期,可作为抗乳腺癌的候选药物。
产品描述
Dracorhodin perchlorate inhibits cell growth, and induces apoptosis in fibroblasts in a dose-and time-dependent manner, arresting cell cycle at G1 phase, may as a candidate for anti-breast cancer. Dracorhodin perchlorate can inhibit high glucose-induced serum and glucocorticoid induced protein kinase 1 (SGK1) and fibronectin(FN) expression in human mesangial cells, and this may be part of the mechanism of preventing and treating renal fibrosis of DN.
Cas No.
125536-25-6
分子式
C17H15ClO7
分子量
366.75
别名
Dracohodin perochlorate;血竭素高氯酸盐;Dracorhodin perochlorate
储存和溶解度
DMSO:199 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years