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Dehydrocorydaline
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dehydrocorydaline图片
CAS NO:30045-16-0
包装与价格:
包装价格(元)
20 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Dehydrocorydalin
13-Methylpalmatine
脱氢紫堇碱
产品介绍
Dehydrocorydaline是一种生物碱。它调节Bax,BCL-2蛋白表达,激活Caspase-7,Caspase-8,并使PARP失活。它能增强p38 MAPK活化,具有抗炎、抗癌等功效。它具有强大的抗疟疾作用,并具低细胞毒性。

产品描述

1. Dehydrocorydaline exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSCLC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimerization of MyoD and E proteins, thus resulting in MyoD activation and myoblast differentiation. 3. Dehydrocorydaline shows antiplatelet effects, it inhibits thrombin-induced platelet aggregation in a low dose ( IC50= 34.914 ug/mL). 4. Dehydrocorydaline has anti-inflammatory and antinociceptive effects. 5. Dehydrocorydaline inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP.

Cas No.

30045-16-0

分子式

C22H24NO4

分子量

366.436

别名

Dehydrocorydalin;13-Methylpalmatine;脱氢紫堇碱

储存和溶解度

DMSO:66 mg/mL(180.1 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years