您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Sanguisorbigenin
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Sanguisorbigenin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sanguisorbigenin图片
CAS NO:6812-98-2
包装与价格:
包装价格(元)
10 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
3β-Hydroxyurs-12,19-dien-28-oic acid
Tomentosolic acid
地榆皂苷元
Ursa-12,19-dien-28-oic acid
19-Dehydroursolic acid
产品介绍
Sanguisorbigenin 抑制耐甲氧西林金黄色葡萄球菌,是一种天然抗菌剂。

产品描述

Sanguisorbigenin is a natural antimicrobial agent that inhibits methicillin-resistant Staphylococcus aureus (MRSA).

体外活性

Treatment of Sanguisorbigenin with sub-MIC concentrations (1.56-6.25 μg/mL) significantly inhibited the expression of blaR1, mecA, and blaZ in MRSA dose-dependently. The gene expression of mecA is remarkably reduced after the treatment of Sanguisorbigenin. The minimal inhibitory concentration values of Sanguisorbigenin against six strains of S. aureus are in the range of 12.5-50 μg/mL[1]. Sanguisorbigenin has a potent antibacterial effect and could effectively reverse the sense of antibiotics by inhibiting the mecA expression and decreasing PBP2a expression[1].

Cas No.

6812-98-2

分子式

C30H46O3

分子量

454.68

别名

3β-Hydroxyurs-12,19-dien-28-oic acid;Tomentosolic acid;地榆皂苷元;Ursa-12,19-dien-28-oic acid;19-Dehydroursolic acid

储存和溶解度

DMSO:60 mg/ml (127.48 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years