Trimetazidine-N-oxide is the major active metabolite of Trimetazidine. Trimetazidine is a specific long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM. Trimetazidine is an effective antianginal agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. References: [1]. Sigmund G, et al. Doping control analysis of trimetazidine and characterization of major metabolites using mass spectrometric approaches. Drug Test Anal. 2014 Nov-Dec;6(11-12):1197-205.
纯度:≥98%
CAS:1644530-89-1