Oleonuezhenide 分离自 Fructus Ligustri Lucidi 中，具有神经保护活性。

Oleonuezhenide is a natural product from Chinese formula Ligustrum lucidum, exerts neuroprotective effects and also considered as treatment of osteoporosis.

Oleonuezhenide elevated casein kinase 2-alpha (CK2α) expression, resulting in β-catenin and Runx2 nuclear translocation. Oleonuezhenide protects bone marrow mesenchymal stem cells by relieved wedelolactone-induced cytotoxicity and maintained osteoblastic activity.

In ovariectomized mice, administration of wedelolactone and oleonuezhenide prevented ovariectomy-induced bone loss by enhancing osteoblastic activity.

112693-21-7

C48H64O27

1073.01

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years